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Microscope Introduction

1. Intro

Learn more about microscope

2. Basics

What: Tool for magnifying small objects, visible to the human eye

Type:

  • Optical: most common, use visible light and a system of lenses to magnify images. Eyepiece, objective lens, light source. Max 1000x due to wavelength of light, limiting the resolution to about 200 nm
  • Stereo: provide 3D view of the specimen. Two eyepieces and lower magnification. For which 3d visualization is beneficial. Not suitable for viewing very small specimen
  • Electron: TEM and SEM
  • Confocal: use laser light to scan sample sequentially
  • Fluorescence: exploit fluorescence and phosphorescence to study properties of organic substances

3. Components

Objective lens: primary lenses, ranging from 4x to 100x

Eyepiece: lens you look through at the top, magnifies the image again, ranging from 10x or 15x

Stage: platform where slides holding specimen are placed

Illuminator: steady, focused light source used to illuminate the specimen

Condenser: located below the stage, focuses the light to control the amount of light

Magnification: Objective lens X eyepiece

4. Digital Microscopy